Circular RNA (circRNA) is a type of non-coding RNA that forms a covalently closed continuous loop. The expression pattern of circRNA varies among cell types and tissues, and many circRNAs are aberrantly expressed in various cancers. Aberrantly expressed circRNAs have ...
Read More »Circular RNAs and exosomes in cancer
Circular RNAs (CircRNAs) are a type of non-coding RNAs (NcRNAs) with a closed annular structure. Until next-generation sequencing (NGS) is developed, the misunderstanding of circRNAs ‘splicing error’ has...
Read More »circRNAs more abundant in exosomes than cells
Recent studies have shown that circular RNAs (circRNAs) are abundant, widely expressed in mammals, and can display cell-type specific expression. However, how production of circRNAs is regulated and their precise biological function remains largely unknown. To study how circRNAs might ...
Read More »Circular RNA is enriched and stable in exosomes
Researchers from Fudan University show for the first time the presence of abundant circRNAs in exosomes. RNA-seq analyses revealed that circRNAs were enriched in exosomes compared to the producer cells. circRNAs are enriched and stable in exosomes and may serve ...
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