Extracellular vesicles (EVs) are important mediators of intercellular communication. Their role in disease processes, uncovered mostly over the last two decades, makes them potential biomarkers, leading to a need to fundamentally understand EV biology...
Read More »An ultrasensitive electrochemical aptasensor for the determination of tumor exosomes based on click chemistry
Exosomes, lipid bilayer membrane vesicles, can guide various pathological and physiological processes. However, reliable, convenient and sensitive methods for exosome determination for early...
Read More »A catalytic molecule machine-driven biosensing method for amplified electrochemical detection of exosomes
Exosomes that carry abundant information have attracted increasing attention as potent biomarkers of liquid biopsy and ideal candidates for early diagnosis and treatment of cancers. Shanghai University...
Read More »Metabolic labeling strategy for exosome tracking
Exosomes are nano-sized vesicles derived from the fusion of multivesicular bodies with the surrounding plasma membrane. Exosomes have various diagnostic and therapeutic potentials in cancer and...
Read More »Surface Functionalization of Exosomes Using Click Chemistry
Researchers at the University of Colorado, Denver have developed a method for conjugation of ligands to the surface of exosomes using click chemistry. Copper-catalyzed azide alkyne cycloaddition (click chemistry) is ideal for biocojugation of small molecules and macromolecules to the ...
Read More »