Exosomes are increasingly designed for drug or functional nucleic acid delivery due to their properties, thereby improving the effectiveness of cancer therapy. The results of this study show that...
Read More »Integrated analysis of exosomal protein biomarkers on A/C electrokinetic chips
Pancreatic ductal adenocarcinoma (PDAC) typically has nonspecific symptoms and is often found too late to treat. Because diagnosis of PDAC involves complex, invasive, and expensive procedures, screening populations at increased risk will depend on...
Read More »Isolation and Identification of miRNAs in exosomes derived from serum of colon cancer patients
Researchers at the Beijing Friendship Hospital used ExoQuick-TC™ Exosome Precipitation Solution to isolate exosomes from the serum of colon cancer patients and identify RNAs in the small vesicles. The shapes of exosomes were observed under a transmission electron microscope. Mass ...
Read More »circRNAs more abundant in exosomes than cells
Recent studies have shown that circular RNAs (circRNAs) are abundant, widely expressed in mammals, and can display cell-type specific expression. However, how production of circRNAs is regulated and their precise biological function remains largely unknown. To study how circRNAs might ...
Read More »Deep Sequencing of RNA from Three Different Extracellular Vesicle (EV) Subtypes Released from Colon Cancer
Secreted microRNAs (miRNAs) enclosed within extracellular vesicles (EVs) play a pivotal role in intercellular communication by regulating recipient cell gene expression and affecting target cell function. Here, researchers from La Trobe University, Australia report the isolation of three distinct EV ...
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