Research involving cytokines and how they’re packaged sheds light on inflammation in asthma, COPD, COVID-19 Inflammatory lung diseases such as asthma, COPD and, most recently, COVID-19...
Read More »A new understanding of the packaging of cytokines in exosomes reveals new strategy to block chronic lung disease
A new study demonstrates that in addition to raining down directly into tissues and triggering damaging events, cytokines can come packaged in tiny compartments called exosomes, making the packaged...
Read More »Extracellular vesicles in chronic obstructive pulmonary disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterised by chronic inflammation and significant airflow obstruction that is not fully reversible, and is one of the leading causes of morbidity and mortality worldwide. Extracellular...
Read More »Activated PMN exosomes are pathogenic entities that cause destruction in the COPD lung
University of Alabama at Birmingham researchers have found a novel, previously unreported pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in the lungs of patients with chronic obstructive pulmonary...
Read More »Cigarette smoke extract induced exosome release
Airway epithelial cells have been described to release extracellular vesicles (EVs) with pathological properties when exposed to cigarette smoke extract (CSE). As CSE causes oxidative stress, researchers from Maastricht University Medical Center investigated whether its oxidative components are responsible for ...
Read More »Extracellular vesicles in lung microenvironment and pathogenesis
Increasing attention is being paid to the role of extracellular vesicles (EVs) in various lung diseases. EVs are released by a variety of cells, including respiratory cells and immune cells, and they encapsulate various molecules, such as proteins and microRNAs, ...
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