A new study demonstrates that in addition to raining down directly into tissues and triggering damaging events, cytokines can come packaged in tiny compartments called exosomes, making the packaged...
Read More »Extracellular Vesicles and Cancer – A Focus on Metabolism, Cytokines, and Immunity
A better understanding of the mechanisms of cell communication between cancer cells and the tumor microenvironment is crucial to develop...
Read More »Extracellular vesicles – lipids as key components of their biogenesis and functions
Intercellular communication has been known for decades to involve either direct contact between cells or to operate by spreading molecules such as,,,
Read More »MicroRNA Profiling of Exosomes Isolated from Biofluids and Conditioned Media
Exosomes are membrane-bound 50-100 nm vesicles released from many cell types including normal and tumorous tissues. Exosomes transport mainly miRNAs, mRNAs, enzymes, cytokines, etc. from the cells of origin to the neighbor cells mediating the communication between them.The content of ...
Read More »Novel insights into exosome-induced, tumor-associated inflammation and immunomodulation
The immune system of cancer patients is often suppressed. Accumulating evidence suggests that exosomes released from tumor cells may play an essential role in this process but the mechanisms are not fully understood. Here the authors review recent papers showing ...
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