Exosomes represent a new generation of biomarkers for the early diagnosis of hepatic carcinoma. Researchers from Tongji Medical College have developed a fluorometric assay that is based on the hybridization chain reaction and magnetic...
Read More »MicroRNAs and exosomes as new diagnostic and therapeutic biomarkers in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is known as a progressive lung disease and the fourth leading cause of death worldwide. Despite valuable efforts, there is still no accurate diagnostic and prognostic tool for COPD. Hence, it seems that finding new ...
Read More »Wake Forest study – adding liquid biopsy improves cancer diagnosis, treatment
Adding a blood test called liquid biopsy to a standard tissue biopsy could significantly improve the accuracy of diagnosis and treatment for patients with cancer, according to researchers at Wake Forest Baptist Medical Center. Their recommendation is...
Read More »Exosome uptake by host cells is most promising for tailored exosomes as drug transporter
Exosomes (Exo), powerful intercellular communicators, are recovered in all body fluids, suggesting suitability for diagnosis and prognosis. Easy in vitro manipulation recommends Exo as drug vehicles. Aiming to consolidate diagnostic and therapeutic potential of Exo, researchers from the University Hospital of ...
Read More »Soon we’ll be able to spot diseases like cancer before we even feel sick
from The Gaurdian by Gustavo Stolovitzky – The sooner a disease is diagnosed, the more likely it is to be well managed or cured. The challenge to finding a disease early is that most of us don’t seek treatment until ...
Read More »Beyond Breast Cancer Awareness Month – Isolating Early Evidence Of Cancer To Aid Diagnostics
from IBM Voice at Forbes.com by Joshua T. Smith, Ph.D., IBM Research – Next time you’re seated at a table over dinner with four of your friends, pause for a moment and consider the following: statistically, it’s likely that two ...
Read More »Researchers Investigate the Utility of Liquid Biopsy for Cancer Diagnosis
Use of circulating tumour DNA (ctDNA) as a liquid biopsy has been proposed for potential identification and monitoring of solid tumours. Researchers from the Wellcome Trust Centre for Human Genetics investigate a next-generation sequencing approach for mutation detection in ctDNA ...
Read More »Simultaneous and multiplexed detection of exosome microRNAs using molecular beacons
Exosomes are small extracellular vesicles that contain biomarker miRNAs from parental cells. Because they circulate throughout bodily fluids, exosomal biomarkers offer great advantages for diagnosis in many aspects. In general, PCR-based methods can be used for exosomal miRNA detection but ...
Read More »New Study Shows Potential for Liquid Biopsies
from Drug Discovery & Development by Ryan Bushey The annual American Society of Clinical Oncology (ASCO) meeting started Saturday in Chicago with news that there could be a viable alternative to tissue biopsies coming down the pipeline. Guardant Health, a ...
Read More »Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis
Gastric cancer (GC) is the fourth most common cancer and the third leading cause of cancer mortality worldwide. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are the most popular non-coding RNAs in cancer research. To date, the roles of miRNAs ...
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