ILIAS Biologics, a global leader in exosome-based therapeutics, announced today that the Company has been granted a key exosome engineering patent by the United States Patent and Trademark Office (USPTO).A patent for ILIAS's exosome engineering was...
Read More »Hartwell Award researcher will pursue use of exosomes that encapsulate RNAi as an effective means to deliver cancer therapy
Soojung Claire Hur, the Clare Boothe Luce Assistant Professor of Mechanical Engineering, was selected by The Hartwell Foundation to receive a 2019 Hartwell Individual Biomedical Research Award. The award...
Read More »Exosomes – from garbage bins to translational medicine
Exosomes are lipid bilayer-enclosed vesicles of endosomal origin, which initially considered as garbage bins to dispose unwanted cellular components, but they are now emerged as an...
Read More »The Role of Exosomes in Metastasis and Progression of Melanoma
The mechanisms of melanoma metastasis have been the subject of extensive research for decades. Improved diagnostic and therapeutic strategies are...
Read More »Extracellular vesicles – a possible theranostic platform strategy for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third highest cause of mortality from cancer, largely because of delays in...
Read More »Extracellular Vesicles As Nanomedicine – Hopes And Hurdles In Clinical Translation
The clinical development of cell therapies is revealing that extracellular vesicles (EVs) may become very instrumental as subcellular therapeutic adjuncts in human medicine. EVs are released by various types of cells, grown in culture, such as...
Read More »The challenges and possibilities of extracellular vesicles as therapeutic vehicles
Extracellular vesicles (EVs) are small lipid-enclosed particles that can carry various types of cargo, including proteins, nucleic acids and metabolites...
Read More »Decoy exosomes as a novel biologic reagent to antagonize inflammation
Exosomes are ubiquitous naturally secreted stable nanovesicles that can be engineered to target and deliver novel therapeutics to treat a host of human...
Read More »Exosomes role in tumorigenesis and anticancer drug resistance
Exosomes are a class of extracellular vesicles ranging in size from 40 to 100 nm, which are secreted by both cancer cells and multiple stromal cells in the tumor microenvironment. Following their secretion, exosomes partake in endocrine, paracrine and autocrine signaling. ...
Read More »Targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity
The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced in 2011 and has since then gained increasing attention as promising new candidates in the field. Targeting EVs to areas of disease can be achieved through ...
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