IMAGE: Tumor suppressor p53 trimer and DNA fragment. Credit: Cho, Y., Gorina, S., Jeffrey, P.D., Pavletich, N.P.; Astrojan. Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer ...
Read More »Clinical relevance of circulating cell-free microRNAs in ovarian cancer
Ovarian cancer is the leading cause of death among gynecologic malignancies. Since ovarian cancer develops asymptomatically, it is often diagnosed at an advanced and incurable stage. Despite many years of research, there is still a lack of reliable diagnostic markers ...
Read More »Benchtop isolation and characterization of functional exosomes by sequential filtration
Early and minimally invasive detection of malignant events or other pathologies is of utmost importance in the pursuit of improved patient care and outcomes. Recent evidence indicates that exosomes and extracellular vesicles in serum and body fluids can contain nucleic ...
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