Celularity is NJ-based biotechnology start-up company striving to become the leader in cellular therapeutics. We are looking for a highly motivated research associate scientist to a group of researchers evaluating novel cell therapies in the field of stem...
Read More »The levels of tumor biomarkers expressed by exosomes may represent a novel, non-invasive clinical tool for the screening and early diagnosis of prostate cancer
Prostate specific antigen (PSA) test is the most common, clinically validated test for the diagnosis of prostate cancer (PCa). While neoplastic lesions of the prostate may cause aberrant levels of PSA in the blood, the quantitation of free or complexed ...
Read More »A double-filtration microfluidic device for isolation and detection of extracellular vesicles
Extracellular vesicles (EVs), including exosomes and microvesicles, are present in a variety of bodily fluids, and the concentration of these sub-cellular vesicles and their associated biomarkers (proteins, nucleic acids, and lipids) can be used to aid clinical diagnosis. Although ultracentrifugation ...
Read More »Exosomal proteins as prostate cancer biomarkers in urine
Exosomes have recently appeared as a novel source of non-invasive cancer biomarkers since tumor-specific molecules can be found in exosomes isolated from biological fluids. Researchers from Oslo University Hospital have previously analyzed the proteome of urinary exosomes by mass spectrometry, ...
Read More »A rapid lateral flow immunoassay test for detection of exosomes previously enriched from cell culture medium and body fluids
Exosomes are cell-secreted nanovesicles (40-200 nm) that represent a rich source of novel biomarkers in the diagnosis and prognosis of certain diseases. Despite the increasingly recognized relevance of these vesicles as biomarkers, their detection has been limited due in part ...
Read More »Immuno-based detection of extracellular vesicles in urine as diagnostic marker for prostate cancer
Extracellular vesicles (including the subclass exosomes) secreted by cells contain specific proteins and RNA that could be of interest in determining new markers. Isolation/characterization of PCa-derived exosomes from bodily fluids enables us to discover new markers for this disease. Unfortunately, ...
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