Tag Archives: EMT

Therapy resistance can arise within tumor cells because of genetic or phenotypic changes (intrinsic resistance), or it can be the result of an interaction with the tumor microenvironment (extrinsic...

The highlights of cancer research include the discovery of exosomes, which are small (30-100 nm) sized vesicular nanoparticles released virtually by all cells. Tumor-derived exosomes (TDEs) are notoriously known for orchestrating the invasion-metastasis cascade via systemic pathways...

Exosomes are small membrane vesicles with a size ranging from 40-100nm. They can serve as functional mediators in cell interaction leading to cancer metastasis. Most studies of the pathogenesis of metastasis focus on genetic or phenotypic changes of the cancer ...