Tag Archives: endosome

Membrane-coupled RNA transport is an emerging theme in fungal biology. Researchers from Heinrich Heine University Düsseldorf review the RNA cargo and mechanistic details of transport via two inter-related sets of organelles: endosomes and extracellular...

Exosomes are secreted extracellular vesicles that mediate intercellular transfer of cellular contents and are attractive vehicles for therapeutic delivery of bimolecular cargo such as nucleic acids, proteins, and even drugs. Efficient exosome-mediated delivery in vivo requires targeting vesicles for uptake ...

Conditions resulting from loss of cellular homeostasis, including oxidative stress, inflammation, protein aggregation, endoplasmic reticulum stress, metabolic stress, and perturbation of mitochondrial function, are common to many pathological disorders and contribute to aging. Cells face these stress situations by engaging ...