Exosomes are 40- to 100- nm cell-originated vesicles derived from endocytic compartments that are released into almost all biological fluids. Exosomes are cell-created vesicles that inherit identical...
Read More »An endothelial-to-adipocyte extracellular vesicle axis governed by metabolic state
Researchers at the University of Texas Southwestern Medical Center have uncovered the existence of extracellular vesicle (EV)-mediated signaling between cell types within the adipose tissue (AT) proper. This phenomenon became evident in their...
Read More »Myoferlin is a functional regulator of cancer-derived exosomes
Exosomes are communication mediators participating in the intercellular exchange of proteins, metabolites and nucleic acids. Recent studies have demonstrated that exosomes are characterized by a unique proteomic composition that is distinct from the cellular one. The mechanisms responsible for determining ...
Read More »Cardiac cell-derived exosomes – the holy grail of cardiac medicine
Repair of the damaged cardiac tissue has been considered the holy grail of cardiac medicine driving researchers for years. Myocardial damage in an adult heart leads to widespread cardiomyocyte loss without active replacement of the dead cardiac tissue, ultimately resulting ...
Read More »Microbeads/Q-dots Fluorescence NTA Methods for Analysis of Exosomes Released from Endothelial Cells and Endothelial Progenitor Cells
Exosomes (EXs) are cell-derived vesicles that mediate cell-cell communication and could serve as biomarkers. Here researchers from Wright State University described novel methods for purification and phenotyping of EXs released from endothelial cells (ECs) and endothelial progenitor cells (EPCs) by ...
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