System Biosciences announced today that QIAGEN, a leading global provider of Sample to Insights solutions for molecular diagnostics and life sciences, has signed a non-exclusive, worldwide license for SBI's patented ExoQuick® technology for research use...
Read More »Identification and analysis of exosomes secreted from macrophages
Exosomes were small vesicles secreted by many cells, and they can play an important role in cell signal transductions. Because the diameter of exosomes is about 30-100 nm, it is so difficult to collection them. In this paper, three kinds ...
Read More »Comparing isolation methods of human saliva-derived exosomes
ExoQuick-TC(TM) (EQ), a chemical-based agent designed to precipitate exosomes, was calibrated for use on saliva collected from healthy individuals. The morphological and molecular features of the precipitations were compared with those obtained using the classical, physical-based method of ultracentrifugation (UC). ...
Read More »The impact of disparate isolation methods for extracellular vesicles on downstream RNA profiling
Despite an enormous interest in the role of extracellular vesicles, including exosomes, in cancer and their use as biomarkers for diagnosis, prognosis, drug response and recurrence, there is no consensus on dependable isolation protocols. Now, researchers at Ghent University Hospital ...
Read More »Isolation of urinary exosomes for RNA biomarker discovery
Urinary exosomes are nanovesicles (40-100 nm) of endocytic origin that are secreted into the urine when a multivesicular body fuses with the membrane of cells from all nephron segments. Interest in urinary exosomes intensified after the discovery that they contain ...
Read More »Comparison of serum exosome isolation methods for microRNA profiling
Exosomes are small membrane bound vesicles secreted by most cell types. Exosomes contain various functional proteins, mRNAs and microRNAs (miRNAs) that could be used for diagnostic and therapeutic purposes. Currently, a standard method for serum exosome isolation is differential ultracentrifugation, ...
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