Exosomes that carry abundant information have attracted increasing attention as potent biomarkers of liquid biopsy and ideal candidates for early diagnosis and treatment of cancers. Shanghai University...
Read More »A hydrogel microchip as a tool for studying exosomes in human serum
Exosomes are cell-derived vesicles that are secreted by both normal and cancer cells. Over the last decade, a few studies have revealed that exosomes cross talk and/or influence major tumor-related pathways such as angiogenesis and metastasis involving many cell types ...
Read More »Rapid inertial solution exchange for enrichment and flow cytometric detection of microvesicles
Despite the significant interest and widespread implications of exosomes, their clinical utility has been limited and biological roles obscured due to the difficulty in their isolation. The current gold standard for isolation is a label-free method that involves repeated lengthy ...
Read More »JOVE publishes a series of exosome technique videos
Exosomes: Vesicles secreted from Multivesicular bodies into the extracellular environment when the multivesicular bodies fuse with the Plasma membrane. Multivesicular bodies are formed from Endosomes when they accumulate vesicles (sometimes referred to as “intraluminal vesicles”) from inward budding of the ...
Read More »Detecting Exosomes Specifically With A Multiplexed Device based on Alternating Current Electrohydrodynamic Induced Nanoshearing
Researchers from the University of Queensland report a multiplexed microfluidic device for highly specific capture and detection of multiple exosome targets using a tuneable alternating current electrohydrodynamic (ac-EHD) methodology – referred to as nanoshearing. In this system, electrical body forces ...
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