Tag Archives: gene delivery

Engineered extracellular vesicles delivered full-length DMD mRNA to skeletal muscle, restoring dystrophin production and improving muscle strength without the toxicities associated with viral therapies...

Engineered extracellular vesicles improve AAV delivery, enhance resistance to neutralizing antibodies, and enable single-step transduction...

Extracellular vesicles released by activated T cells transferred DNA to immune and tumor cells, enhancing antigen presentation and strengthening anti-tumor immune responses...

An exosome-based platform uses extracellular vesicles to deliver CAR genes directly to T cells in vivo, enabling rapid generation of tumor...

Loading nucleic acids into EVs has proven to be a challenge. Traditional methods for loading genetic material into EVs are often inefficient and may not...

The low yield of extracellular vesicle (EV) secretion is a major obstacle for mass production and limits their potential for clinical applications as a drug delivery platform. Here, Texas A&M University researchers...

Exosomes, one subpopulation of nanosize extracellular vesicles derived from multivesicular bodies, ranging from 30 to 150 nm in size, emerged as promising carriers for small interfering ribonucleic acid (siRNA) delivery, as they are capable of transmitting molecular messages between cells ...