Exosomes, cell-derived vesicles encompassing lipids, DNA, proteins coding genes and noncoding RNAs (ncRNAs) are present in diverse body fluids. They offer novel biomarker and drug therapy potential for diverse diseases, including cancer. Using gene ontology, exosomal genes database and GeneCards ...
Read More »Exosomes play an important role in the process of psoralen reverse multidrug resistance of breast cancer
Release of exosomes have been shown to play critical roles in drug resistance by delivering cargo. Targeting the transfer of exosomes from resistant cells to sensitive cells may be an approach to overcome some cases of drug resistance. In this ...
Read More »Extending gene ontology in the context of extracellular RNA and vesicle communication
To address the lack of standard terminology to describe extracellular RNA (exRNA) data/metadata, a team led by researchers at Yale University School of Medicine have launched an inter-community effort to extend the Gene Ontology (GO) with subcellular structure concepts relevant ...
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