Tag Archives: Harvard Medical School

Newly recognized as natural nanocarriers that deliver biological information between cells, extracellular vesicles (EVs), including exosomes and microvesicles, provide unprecedented therapeutic opportunities. Large-scale and cost-effective manufacturing is imperative for EV products to meet commercial and clinical demands...

Precise rare-cell technologies require the blood to be processed immediately or be stabilized with fixatives. Such restrictions limit the translation of circulating tumor cell (CTC)-based liquid biopsy assays that provide accurate molecular data in guiding clinical decisions. Here researchers from ...

Gene therapy, the ability to treat a disease at the level of nucleic acid, has journeyed from science fiction, to hard lessons learned from early clinical trials, to improved technologies with efficacy in patients for several diseases. Adeno-associated virus (AAV) ...

Type: Full Time Location: Boston, Massachusetts Job Description: GENERAL SUMMARY/ OVERVIEW STATEMENT: Postdoctoral Position in exosomes in AD and their utility as biomarkers Working jointly in the laboratories of Dominic Walsh and Dennis Selkoe at the Ann Romney Center for ...

NEW YORK (360Dx) – A multiplexed nanoplasmonic assay designed specifically to fit into clinical workflows is taking aim at high-throughput detection of pancreatic ductal adenocarcinoma (PDAC), an aggressive and often inoperable form of pancreatic cancer. Developed by researchers at Harvard ...

Adipose tissue is a major site of energy storage and has a role in the regulation of metabolism through the release of adipokines. Here researchers from the Joslin Diabetes Center and Harvard Medical School, show that mice with an adipose-tissue-specific ...

Exosomes are small packages released by cells into the blood circulation and other body fluids such as urine. These exosomes have been known for a long time, but were not considered very useful for medicine. However, a late night in ...

Extracellular vesicles (EVs) are lipid membrane vesicles released by cells. They carry active biomolecules including DNA, RNA, and protein which can be transferred to recipient cells. Isolation and purification of EVs from culture cell media and biofluids is still a ...

Calcifying extracellular vesicles (EVs) released from cells within atherosclerotic plaques have received increased attention for their role in mediating vascular calcification, a major predictor of cardiovascular morbidity and mortality. However, little is known about the difference between this pathologic vesicle ...