The combination of single-cell transcriptomic analysis and plasma RNA sequencing represents an approach for the development of new noninvasive...
Read More »Liquid biopsy in hepatocellular carcinoma
Solid tumors release a variety of cellular components into the bloodstream that can be sampled by liquid biopsy. These blood-borne biomarkers include circulating tumor cells, exosomes, cell-free DNA...
Read More »Extracellular vesicles – a possible theranostic platform strategy for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third highest cause of mortality from cancer, largely because of delays in...
Read More »Exosomes of pasteurized milk – potential pathogens of western diseases
Milk consumption is a hallmark of western diet. According to common believes, milk consumption has beneficial effects for human health. Pasteurization of cow's milk protects thermolabile vitamins and other organic compounds including bioactive and...
Read More »Ymir Genomics and the OHSU Knight Cancer Institute to collaborate on urinary exosomal biomarkers
Ymir Genomics, LLC (Ymir) and the Knight Cancer Institute at Oregon Health & Science University, OHSU, today announced a strategic collaboration to develop urinary biomarkers that will help detect hepatocellular carcinoma (HCC) in at-risk patient populations. The collaboration will exploit ...
Read More »The role of exosomes in treatment of hepatocellular carcinoma (HCC)
Exosomes are nanovesicles that may play a role in intercellular communication by acting as carriers of functional contents such as proteins, lipids, RNA molecules and circulating DNA from donor to recipient cells. In addition, exosomes may play a potential role ...
Read More »Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinoma
Recent studies have shown that circulating microRNAs are a potential biomarker in various types of malignancies. The aim of this study was to investigate the feasibility of using serum exosomal microRNAs as novel serological biomarkers for hepatocellular carcinoma (HCC) in ...
Read More »Combination of exosomes and circulating microRNAs may serve as a promising tumor marker
Due to unsatisfying prognosis of AFP for hepatocellular carcinoma (HCC), researchers from the Chengdu Military General Hospital set out to evaluate the prognostic value of combination of exosomes and miRNAs in detecting HCC. HCC was induced with diethylnitrosamine in rats ...
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