As the second leading cause of cancer morbidity and death in women, cervical cancer remains an important public health problem worldwide. Novel biomarkers with high sensitivity and specificity for the early detection and diagnosis of cervical cancer are urgently needed. ...
Read More »lncRNA in urinary exosomes may serve as biomarkers for bladder cancer
Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA), messenger RNA (mRNA), and long non-coding RNA (lncRNA) from their cells of origin. Although miRNA, protein and ...
Read More »Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes
Long non-coding RNAs (lncRNAs) are involved in regulating chromatin modifications, gene transcription, mRNA translation, and protein function. Researchers from Istanbul University recently reported a high variation in the basal expression levels of a panel of lncRNAs in HeLa and MCF-7 ...
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