Tag Archives: hypoxia

Exosomes are structurally and functionally pleiotropic nano-sized (∼30–150 nm in diameter) extracellular vesicles (EVs) with endosomal origin. These vesicles are secreted by almost all cells and play a significant role in intercellular communication...

Epidemiological studies have illustrated that regular aspirin consumption may decrease the risk of non-small cell lung cancer (NSCLC). Zhujiang Hospital researchers investigated the mechanism of aspirin-induced inhibition of NSCLC development during hypoxia. A549 cells were pre-treated with the vehicle control ...

Extracellular vesicles (EVs) are nanosized particles released by all cells that have been heralded as novel regulators of cell-to-cell communication. It is...

Treating the hypoxic region of the tumor remains a significant challenge. Researchers from Stanford University set out to develop an exosome platform that can target regions of tumor hypoxia and that can be monitored in vivo using magnetic particle...

Cell-to-cell communication between the blastocyst and endometrium is critical for implantation. In recent years, evidence has emerged from studies in humans and several other animal species that exosomes are secreted from the endometrium and trophoblast cells and may play an ...

Exosomes are nano-sized (20-100nm) vesicles released by a variety of cells and are generated within the endosomal system or at the plasma membrane. There is emerging evidence that exosomes play a key role in intercellular communication in ovarian and other ...

Exosomes derived from tumor cells are essential for processes involved in tumor progression, including angiogenesis, tumor cell proliferation and immunoregulation. In addition, exosome secretion may contribute to the mechanisms of hypoxia-induced angiogenesis and metastasis of tumors. In the present study, ...