Astrocyte-derived extracellular vesicles embedded in an injectable scaffold recruited reparative immune cells, promoted blood vessel growth, and improved...
Read More »Understanding the role of extracellular vesicles in neuroinflammation during sepsis
Sepsis is a severe medical condition that occurs when the body's response to infection leads to widespread inflammation. One concerning...
Read More »Extracellular Vesicles and Cancer – A Focus on Metabolism, Cytokines, and Immunity
A better understanding of the mechanisms of cell communication between cancer cells and the tumor microenvironment is crucial to develop...
Read More »Extracellular vesicles could be personalized drug delivery vehicles
Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous — their own — immune cells to ...
Read More »Boosting cancer vaccines with extracellular vesicle-internalizing receptors
Researchers at EPFL have created artificial molecules that can help the immune system to recognize and attack cancer tumors. The study is published in...
Read More »Tumor-derived exosomes regulate expression of immune function-related genes in human T cells
Tumor cell-derived exosomes (TEX) suppress functions of immune cells. Here, changes in the gene profiles of primary human T lymphocytes exposed in vitro to exosomes were evaluated. CD4(+) Tconv, CD8(+) T or CD4(+) CD39(+) Treg were isolated from normal donors’ ...
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