Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) causes severe acute respiratory syndrome. mRNA vaccines directed at the SARS-CoV-2 spike protein resulted in development of Abs and...
Read More »Shedding light on the role of extracellular vesicles in HIV infection and wound healing
Extracellular vesicles (EVs) play an important role in intercellular communication. They are naturally released from cells into the extracellular environment. Based on their biogenesis, release pathways, size, content, and function, EVs are classified into exosomes, microvesicles (MVs), and apoptotic bodies ...
Read More »Exosomes and immune response in cancer
Exosomes are a type of extracellular vesicle whose study has grown exponentially in recent years. This led to the understanding that these structures, far from being inert waste by-products of cellular functioning, are active players in intercellular communication mechanisms, including ...
Read More »Exosome RNA regulates immmune response to flu virus infection
Exosomes regulate cell-cell communication by transferring functional proteins and RNAs between cells. Here, to clarify the function of exosomes...
Read More »New Zealand researchers makes ‘natural born killer’ cell discovery
An unexpected role for a white blood cell called the Natural Killer (NK) cell – a critical cell for ridding the body of infection and cancer, has been discovered by researchers at New Zealand’s University of Otago . The NK ...
Read More »Extracellular vesicles – a promising avenue for the detection and treatment of infectious diseases?
Extracellular vesicles (EVs) have gained increasing attention as novel disease biomarkers and as promising therapeutic agents. These cell-derived, phospholipid-based particles are present in many – if not all – physiological fluids. They have been shown to govern several physiological processes, ...
Read More »Isolation and mass spectrometry analysis of urinary extraexosomal proteins
Researchers at the University of Oslo aimed to develop a LC-MS/MS-based proteomic analysis method of urinary exosomal proteins that has the potential to discover disease biomarkers. In short, urinary exosomes from healthy subjects were isolated by immunocapture on magnetic beads, ...
Read More »Donor-derived exosomes induce specific regulatory T cells to suppress immune inflammation
To inhibit the immune inflammation in the allografts can be beneficial to organ transplantation. This study aims to induce the donor antigen specific regulatory T cells (Treg cell) inhibit the immune inflammation in the allograft heart. In this study, peripheral ...
Read More »Exosomes and Their Therapeutic Potentials of Stem Cells
Exosomes, a group of vesicles originating from the multivesicular bodies (MVBs), are released into the extracellular space when MVBs fuse with the plasma membrane. Numerous studies indicate that exosomes play important roles in cell-to-cell communication, and exosomes from specific cell ...
Read More »Exosomes as Immunotheranostic Nanoparticles
Exosomes are small biological membrane vesicles that measure 30 to 100 nm in diameter. They are involved in a wide array of biological activities, such as cell-cell communication, signal transduction, transport of genetic materials, and modulation of immune response. Evidence ...
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