Malignant melanoma (MM), the most lethal skin cancer, is highly invasive and metastatic. These qualities are related to not only genetic mutations in MM itself but also the interaction of MM cells with...
Read More »Emerging prospects of exosomes for cancer treatment
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are secreted by most cells and contain various bioactive molecules reflecting their cellular origin and mediate intercellular communication. Studies of these exosomal features in tumor pathogenesis ...
Read More »Genetically engineered cell-derived nanoparticles for targeted breast cancer immunotherapy
Exosomes are nanosized membranous vesicles secreted by a variety of cells. Due to their unique and pharmacologically important properties, cell-derived exosome nanoparticles have drawn significant interest for drug development. By genetically modifying exosomes with two distinct types of surface-displayed monoclonal ...
Read More »KU researcher wins grant to investigate use of 3D-biomimetic-tissue-engineered exosomes for immunotherapy
A researcher at the University of Kansas has just earned a five-year, $1.89 million National Institutes of Health grant to investigate how 3D-biomimetic-tissue-engineered exosomes might be a new avenue...
Read More »Bioactive nanoparticles for cancer immunotherapy
Currently, immunotherapy is considered to be one of the effective treatment modalities for cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to the interest for research...
Read More »Exosomes – their biogenesis and role in inter-cellular communication, tumor microenvironment and cancer immunotherapy
Exosomes are extracellular vesicles ranging from 30 to 150 nm in diameter that contain molecular constituents of their host cells. They are released from different types of cells ranging from immune to tumor cells and play an important role in intercellular...
Read More »Reversing Cancer with Immunotherapies and Exosomes
Reversing Cancer with Immunotherapies and Exosomes - World Stem Cell Summit - 2018 - Day 3
Read More »Engineered exosomes emerging from muscle cells break the tolerance towards tumor self-antigens
Researchers at the National Center for Global Health, Italy recently described a novel biotechnological platform for the production of unrestricted cytotoxic T lymphocyte (CTL) vaccines. It relies on in vivo engineering of exosomes, i.e., nanovesicles constitutively released by all cells, ...
Read More »Post-doc position available – immunology and immunotherapy of human solid tumors
Position Title Postdoctoral Associate Classification Title Postdoctoral Associate Posting Number R1700228 Employer Research Foundation Appointment Type Position Type Appointment Term Salary Grade E.8 Strategic Strength Posting Detail Information Position Summary We are seeking a Postdoctoral Associate to work on immunology ...
Read More »Penn Studies Find Promise for Innovations in Liquid Biopsies
From using fluid in the lungs to better understand the potential of immunotherapy treatments in lung cancer, to tracking circulating tumor cells in prostate cancer, to conducting RNA sequencing of cancer cell clusters from the blood of pancreatic cancer patients, ...
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