It is a long-standing paradigm in the field of virology that naked viruses cause lysis of infected cells to release progeny virus. However, recent data...
Read More »Exosomes from Plasmodium-infected Hosts Inhibit Tumor Angiogenesis
A research group led by Prof. CHEN Xiaoping from the Guangzhou Institutes of Biomedicine and Health (GIBH) of Chinese Academy of Sciences revealed a new mechanism about exosomes from Plasmodium-infected hosts inhibit tumor angiogenesis. The study was published in Oncogenesis. Malaria infection has been ...
Read More »Herpesviruses hijack host exosomes for viral pathogenesis
Herpesviruses are remarkable pathogens possessing elaborate mechanisms to seize various host cellular components for immune evasion, replication, and virion egress. As viruses are dependent upon their hosts, investigating this intricate interplay has revealed that the exosome pathway is utilized by ...
Read More »Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses
Structure and composition of exosomes. Exosomes contain a plasma membrane-derived phospholipid bilayer membrane. The composition depends on the cell type of origin, state of health of the host, and extracellular stimuli. Exosome contents include mRNA, miRNA, DNA, and proteins like ...
Read More »Exosomes from Hepatitis C Infected Patients Contain Replication Competent Viral RNA
Since its first isolation and identification in 1989, Hepatitis C virus (HCV), has caused significant disease burden to humans worldwide. So far, there is no vaccine against HCV, and neutralizing antibody therapies to block receptor–mediated transmission of HCV to liver ...
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