Tag Archives: Intraluminal vesicles

Q&A: What are exosomes, exactly?

exosomes

What is the current definition of an exosome? That is a very good question. Since the original description of exosomes over 30 years ago, the term has been loosely used for various forms of extracellular vesicle, muddying the field and ...

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Mechanisms of RNA loading into exosomes

exosome rna

Upon fusion of multivesicular bodies (MVBs) with the plasma membrane, intraluminal vesicles (ILVs) are released into the extracellular space as exosomes. Since the lipid composition of the exosomal membrane resembles that of raft microdomains, the inward budding process involves the ...

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