The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced in 2011 and has since then gained increasing attention as promising new candidates in the field. Targeting EVs to areas of disease can be achieved through ...
Read More »Extracellular vesicles as biological shuttles for targeted therapies
The development of effective nanosystems for drug delivery represents a key challenge for the improvement of most current anticancer therapies. Recent progress in the understanding of structure...
Read More »Induction of lipid droplets in non-macrophage cells as well as macrophages by liposomes and exosomes
It has been reported that phospholipid nanoparticles (PNPs) including liposomes and exosomes could efficiently induce lipid droplets (LDs) in macrophages. However, in non-macrophage cells, the effects of...
Read More »Bioactive nanoparticles for cancer immunotherapy
Currently, immunotherapy is considered to be one of the effective treatment modalities for cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to the interest for research...
Read More »Strategic design of extracellular vesicle drug delivery systems
Extracellular vesicles (EVs), nanoscale vectors used in intercellular communication, have demonstrated great promise as natural drug delivery systems. Recent reports have detailed impressive in vivo...
Read More »Methylcellulose-based method for visualization of exosomes
Synthetic and naturally occurring lipid-rich nanoparticles are of wide ranging importance in biomedicine. They include liposomes, bicelles, nanodiscs, exosomes and virus particles. The quantitative study of these particles requires methods for high-resolution visualization of the whole population. One powerful imaging ...
Read More »Liposomes, Exosomes, and Virosomes: From Modeling Complex Membrane Processes to Medical Diagnostics and Drug Delivery
Liposomes, Exosomes, and Virosomes: From Modeling Complex Membrane Processes to Medical Diagnostics and Drug Delivery Ascona, Switzerland, September 11-16, 2016 This meeting will cover recent developments for investigating biochemical reactions and networks at, in, and across membranes of artificial and ...
Read More »Engineering hybrid exosomes by membrane fusion with liposomes
Exosomes are a valuable biomaterial for the development of novel nanocarriers as functionally advanced drug delivery systems. To control and modify the performance of exosomal nanocarriers, researchers at Kyoto University Katsura developed hybrid exosomes by fusing their membranes with liposomes ...
Read More »Possibilities and limitations of current technologies for quantification of biological extracellular vesicles
Nano-sized extracelullar vesicles (EVs) released by various cell types play important roles in a plethora of (patho)physiological processes and are increasingly recognized as biomarkers for disease. In addition, engineered EV and EV-inspired liposomes hold great potential as drug delivery systems. ...
Read More »Current technologies for quantification of biological extracellular vesicles and synthetic mimics – possibilities and limitations
Nano-sized Extracelullar vesicles (EVs) released by various cell types play important roles in a plethora of (patho)physiological processes and are increasingly recognized as biomarkers for disease. In addition, engineered EV and EV-inspired liposomes hold great potential as drug delivery systems. ...
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