Engineered extracellular vesicles offer promising drug delivery capabilities, but decades of liposome research provide important lessons for overcoming...
Read More »Extracellular vesicle-inspired liposomes boost immune response against pathogen antigens
Extracellular vesicles inspired synthetic liposomes enhance antigen uptake and antibody responses, providing a potentially scalable platform for...
Read More »Targeted caffeine delivery using exosome hybrids to treat liver fibrosis
Engineered extracellular vesicles carrying caffeine and magnetic liposomes improved liver targeting and reduced fibrosis markers in rats, highlighting a...
Read More »The invisible bubbles that spread cancer could also help stop it
Extracellular vesicles and exosome-like liposomes reveal how cancer spreads and offer new nanomedicine strategies to block metastasis and improve targeted therapies...
Read More »Translating extracellular vesicle insights to biomimetic vesicles for biomedical use
Excerpt: Biomimetic synthetic vesicles, inspired by extracellular vesicles, combine biocompatibility with scalability to improve drug delivery and regenerative medicine. This review explores their design, advantages, and potential biomedical applications...
Read More »Targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity
The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced in 2011 and has since then gained increasing attention as promising new candidates in the field. Targeting EVs to areas of disease can be achieved through ...
Read More »Extracellular vesicles as biological shuttles for targeted therapies
The development of effective nanosystems for drug delivery represents a key challenge for the improvement of most current anticancer therapies. Recent progress in the understanding of structure...
Read More »Induction of lipid droplets in non-macrophage cells as well as macrophages by liposomes and exosomes
It has been reported that phospholipid nanoparticles (PNPs) including liposomes and exosomes could efficiently induce lipid droplets (LDs) in macrophages. However, in non-macrophage cells, the effects of...
Read More »Bioactive nanoparticles for cancer immunotherapy
Currently, immunotherapy is considered to be one of the effective treatment modalities for cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to the interest for research...
Read More »Strategic design of extracellular vesicle drug delivery systems
Extracellular vesicles (EVs), nanoscale vectors used in intercellular communication, have demonstrated great promise as natural drug delivery systems. Recent reports have detailed impressive in vivo...
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