Liquid biopsy-based biomarkers, such as microRNAs, represent valuable tools for patient management, but often do not make it to integration in the clinic...
Read More »Genetic ‘weather forecasting’ based on liquid biopsies could predict bowel cancer’s response to treatment
Blood tests could predict how long it takes until bowel cancer returns based on the same principle used in forecasting the weather, a new study has found. The blood tests, or ‘liquid biopsies’, could also...
Read More »Protein cancer biomarkers in circulating exosomes
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from which they originated, reflecting the ...
Read More »Isolating exosomes for cancer diagnostics
from Technology Networks by Anna MacDonald – Once considered cellular rubbish, exosomes are now known to play important roles in cellular communication. These small messengers are defined as “extracellular vesicles that are released from cells upon fusion of an intermediate ...
Read More »Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients
Detection of circulating tumor DNA (ctDNA) can be limited due to their relative scarcity in circulation, particularly while patients are actively undergoing therapy. Exosomes provide a vehicle through which cancer-specific material can be enriched from the compendium of circulating non-neoplastic ...
Read More »Lonza Invests to Develop Exosomes for Next-Generation Life-Science Applications
Lonza has acquired HansaBioMed Life Sciences and has invested into Exosomics Siena to develop next-generation research, therapeutic and diagnostic applications based on exosomes Exosomes technology will leverage Lonza’s portfolio of drug discovery products, as well as its development and manufacturing ...
Read More »Agena Bioscience Introduces New Lung and Colon Cancer Panels for Detection of Somatic Mutations from Liquid Biopsies
Agena Bioscience today introduced new targeted research panels for the detection of somatic mutations from lung and colon cancers. The UltraSEEK™ Lung and Colon Panels enable detection of mutations as low as 0.1% minor allele frequency (MAF) from circulating tumor ...
Read More »Vesicle formation findings could pave way for liquid biopsies, drug delivery devices
A schematic illustration of vesicle formation via self-assembly. Driven by hydrophobic interaction along the free edge, a planar circular membrane patch (A) curves into a spherical cap (B and C) and eventually closes to form a vesicle (D). Only cross-sections ...
Read More »Exosomal microRNAs in liquid biopsies: future biomarkers for prostate cancer
Prostate cancer is the second most diagnosed cancer in males in the world. Plasma quantification of prostate-specific antigen substantially improved the early detection of prostate cancer, but still lacks the required specificity. Clinical management of prostate cancer needs advances in ...
Read More »Exosomal microRNAs in liquid biopsies
Prostate cancer is the second most diagnosed cancer in males in the world. Plasma quantification of prostate-specific antigen substantially improved the early detection of prostate cancer, but still lacks the required specificity. Clinical management of prostate cancer needs advances in ...
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