This new study explores the utility and potential of noninvasive liquid biopsies as a method of early detection in lung cancer. Despite the known...
Read More »Mutational status of plasma exosomal KRAS predicts the outcome in patients with metastatic colorectal cancer
Liquid biopsy has become a useful alternative in metastatic colorectal cancer (mCRC) patients when tissue biopsy of metastatic sites is not feasible. In this study researchers at the Catholic University of Sacred Heart aimed to investigate the clinical utility of ...
Read More »Biomarkers of cancer cell-derived extracellular vesicles from liquid biopsies
Tumor-secreted extracellular vesicles (EVs) are the main mediators of cell-cell communication, permitting cells to exchange proteins, lipids, and...
Read More »Urine exosome-based liquid biopsy test can can detect and risk-classify prostate cancer with over 90% accuracy
The miR Sentinel Prostate Cancer Test is a non-invasive molecular test based on the analysis of small non-coding RNAs (sncRNA) isolated from non-DRE urinary exosomes. It provides an innovative...
Read More »Single Cell and Plasma RNA Sequencing for RNA Liquid Biopsy for Hepatocellular Carcinoma
The combination of single-cell transcriptomic analysis and plasma RNA sequencing represents an approach for the development of new noninvasive...
Read More »UH researcher receives NIH grant to detect cancer biomarkers in blood by counting exosomes
University of Houston Researcher Receives $2.7M Grant to Develop Test with ‘Unprecedented Early Detection Power’ Liquid biopsy...
Read More »Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes
Traumatic brain injury (TBI) is a global cause of morbidity and mortality. Initial management and risk stratification of patients with TBI is made difficult by the relative insensitivity of screening radiographic studies as well as by the absence of a ...
Read More »Study focuses on a different kind of liquid biopsy to detect cancer
Because cancer is easier to successfully treat when it's caught early, a major goal in cancer research is to develop new ways to find tumors at early stages, before they start to spread. One approach...
Read More »Liquid biopsy-based exo-oncomiRNAs can predict prostate cancer aggressiveness
Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...
Read More »Extracellular RNAs as potential biomarkers for cancer
The discovery that all cells secrete extracellular vesicles (EVs) to shuttle proteins and nucleic acids to recipient cells suggested they play an important role in intercellular communication. EVs are widely distributed in many body fluids, including blood, cerebrospinal fluid, urine ...
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