Exosomes are nanovesicles that may play a role in intercellular communication by acting as carriers of functional contents such as proteins, lipids, RNA molecules and circulating DNA from donor to recipient cells. In addition, exosomes may play a potential role ...
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Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly due to delayed detection. We hypothesized that intercellular communication is critical for metastatic progression. Here, researchers from the Weill Cornell Medical College show that PDAC-derived exosomes induce liver pre-metastatic ...
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Serum exosomal microRNAs (miRNAs) have received considerable attention as potential biomarkers for diagnosing cancer. The canonical technique for measuring miRNA transcript levels is reverse transcription quantitative polymerase chain reaction (RT-qPCR). One prerequisite for validating RT-qPCR data is proper normalization with ...
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Uveal melanoma is a tumour arising from melanocytes of the eye, and 30 per cent of these patients develop liver metastases. Exosomes are small RNA containing nano-vesicles released by most cells, including malignant melanoma cells. This clinical translational study included ...
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Like most cell types, hepatocytes constantly produce extracellular vesicles (EVs) such as exosomes and microvesicles that are released into the circulation to transport signaling molecules and cellular waste. Circulating EVs are being vigorously explored as biomarkers of diseases and toxicities, ...
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The liver is a complicated environment comprised of several different cell types such as hepatocytes, parenchymal cells, Kupffer cells, natural killer cells, B cells, T cells, and stellate cells, which are involved in various functions necessary for maintaining of the ...
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The liver is a complicated environment comprised of several different cell types such as hepatocytes, parenchymal cells, Kupffer cells, natural killer cells, B cells, T cells, and stellate cells, which are involved in various functions necessary for maintaining of the ...
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Exosome RNA Exosome RNA Research & Industry News
