Exosome-mediated transfer of regulatory RNAs is a key feature that enables cancer cells to shape a tumor-promoting environment. Cancers growing in the bone can use this communication modality to...
Read More »Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment
Exosomes are extracellular vesicles released by many cell types and have been attributed for their roles in many diseases including cancer. Exosomes...
Read More »RNA in extracellular vesicles
Cells release a range of membrane-enclosed extracellular vesicles (EVs) into the environment. Among them, exosomes and microvesicles (collectively measuring 40-1000 nm in diameter) carry proteins, signaling lipids, and nucleic acids from donor cells to recipient cells, and thus have been ...
Read More »Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes
Long non-coding RNAs (lncRNAs) are involved in regulating chromatin modifications, gene transcription, mRNA translation, and protein function. Researchers from Istanbul University recently reported a high variation in the basal expression levels of a panel of lncRNAs in HeLa and MCF-7 ...
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