Tag Archives: Massachusetts General Hospital

Extracellular vesicles (EVs), including exosomes, are nanoscale membrane particles shed from cells and contain cellular proteins whose makeup could inform cancer diagnosis and treatment. Most analyses have focused on surface proteins while analysis of...

Potential biomarkers could help monitor treatment response, guide clinical decisions A new microfluidic device developed by investigators at Massachusetts General Hospital (MGH) may help realize the potential of tumor-derived extracellular vesicles (EVs) – tiny lipid particles that carry molecules through ...

NEW YORK (360Dx) – A multiplexed nanoplasmonic assay designed specifically to fit into clinical workflows is taking aim at high-throughput detection of pancreatic ductal adenocarcinoma (PDAC), an aggressive and often inoperable form of pancreatic cancer. Developed by researchers at Harvard ...

GENERAL SUMMARY/ OVERVIEW STATEMENT: The Research Fellow is a full-time position under the direction of the Principal Investigator. Primary responsibilities are to work independently to design, organize and carry out experiments for research projects under the direction of the PI ...

Research Fellow, Surgical Oncology – (3013511) GENERAL SUMMARY/ OVERVIEW STATEMENT: The Research Fellow is a full-time position under the direction of the Principal Investigator. Primary responsibilities are to work independently to design, organize and carry out experiments for research projects ...

Adeno-associated virus (AAV) vectors are showing promise in gene therapy trials and have proven to be extremely efficient biological tools in basic neuroscience research. One major limitation to their widespread use in the neuroscience laboratory is the cost, labor, skill, ...

Extracellular vesicles, including exosomes, are nanoscale vesicles that carry molecular information of parental cells. They are being pursued as biomarkers of cancers that are difficult to detect or serially follow. Here researchers from Massachusetts General Hospital present a compact sensor ...

Real-time monitoring of drug efficacy in glioblastoma multiforme (GBM) is a major clinical problem as serial re-biopsy of primary tumours is often not a clinical option. MGMT (O(6)-methylguanine DNA methyltransferase) and APNG (alkylpurine-DNA-N-glycosylase) are key enzymes capable of repairing temozolomide-induced ...