Alcoholic hepatitis (AH) is diagnosed by clinical criteria, although several objective scores facilitate risk stratification. Extracellular vesicles (EVs) have emerged as novel biomarkers for many diseases and are also implicated in the pathogenesis of AH...
Read More »Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid
Concentration of extracellular vesicles (EVs) from biological fluids in a scalable and reproducible manner represents a major challenge. Mayo Clinic researchers report the use of tangential flow filtration...
Read More »MicroRNA and mRNA cargo of extracellular vesicles
Mesenchymal stromal/stem cells (MSCs) are clinically useful for cell-based therapy, but concerns regarding their ability to replicate limit their human application. MSCs release extracellular vesicles (EVs) that mediate at least in part the paracrine effects of the parental cells. To ...
Read More »The Mayo Clinic uses Nanoparticle Tracking Analysis to Study the Behavior of Exosomes and Microvesicles
NanoSight reports on how Nanoparticle Tracking Analysis, NTA, is being used to study extracellular vesicles in the research laboratories of Dr. Gregory Gores of the Mayo Clinic in Rochester, Minnesota. The Gores Laboratory of the Mayo Clinic does basic research ...
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