Tag Archives: Melanoma

The mechanisms of melanoma metastasis have been the subject of extensive research for decades. Improved diagnostic and therapeutic strategies are...

Tumor-derived extracellular vesicles (TEV) “educate” healthy cells to promote metastases. Researchers from the University of Pennsylvania found that melanoma TEV downregulated type I interferon (IFN)...

Exosomes (Exo) are small vesicles produced by melanoma cells and the accessory cells of the tumor microenvironment. They emerge via both classical and direct pathways and actively participate in tumor colonisation of distant tissues. The proteins, nucleic acids, cytokines and ...

Tumour-derived exosomes (TEX) are a subset of extracellular vesicles (EVs) present in body fluids of patients with cancer. The role of this exosome subset in melanoma progression has been of interest ever since ex vivo studies of exosomes produced by ...

Macrophages are key participants in melanoma growth and survival. In general, macrophages can be classified as M1 or M2 activation phenotypes. Increasing evidence demonstrates that melanoma exosomes also facilitate tumor survival and metastasis. However, the role of melanoma exosomes in ...

Exosomes are nanovesicles that are released from normal and tumor cells and are detectable in cell culture supernatant and human biological fluids. Although previous studies have explored exosomes released from cancer cells, little is understood regarding the functions of exosomes ...

Biocartis Group NV , an innovative molecular diagnostics company, today announces the publication in the renowned clinical oncology journal The Lancet Oncology of an important study[1] by Prof. Dr. Bart Neyns from the University Hospital in Brussels (Belgium). In this ...

Liquid biopsy of tumor through isolation of circulating tumor cells (CTCs) allows non-invasive, repetitive, and systemic sampling of disease. Although detecting and enumerating CTCs is of prognostic significance in metastatic cancer, it is conceivable that performing molecular and functional characterization ...

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Exosome Diagnostics, Inc., the world’s only provider of a revolutionary liquid biopsy platform that enables analysis of both living and dying processes of disease states, thus aiming to reduce or eliminate the need for tissue biopsies, today announced ...

New research has identified a novel mode of communication between adipocytes and cancer cells that regulates tumour aggressiveness. Adipocyte exosomes (ad-exos) purified from conditioned medium of 3T3-F442A mature adipocytes increased melanoma cell migration and invasion in vitro. Analysis of the ...