Tag Archives: Melanoma

Extracellular vesicles released by pro-inflammatory macrophages carry cytokines that activate inflammatory signaling in melanoma cells, helping tumors become more invasive and highlighting how...

Melanoma cells deploy extracellular vesicles to disable cytotoxic immune cells, revealing a potent immune-evasion mechanism that exposes new...

Researchers have developed a microneedle patch that detects melanoma by capturing extracellular vesicles directly from the skin, offering a faster, less invasive way to diagnose this deadly cancer...

Scientists at the University of Texas MD Anderson Cancer Center aimed to modify EVs to enhance their ability to stimulate the immune system, especially...

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University...

Malignant melanoma is a serious type of skin cancer that is becoming more common worldwide. While early-stage melanoma can often be treated successfully with surgery, the outlook for patients with advanced melanoma is much less encouraging—only about 20% survive beyond ...

The mechanisms of melanoma metastasis have been the subject of extensive research for decades. Improved diagnostic and therapeutic strategies are...

Tumor-derived extracellular vesicles (TEV) “educate” healthy cells to promote metastases. Researchers from the University of Pennsylvania found that melanoma TEV downregulated type I interferon (IFN)...

Exosomes (Exo) are small vesicles produced by melanoma cells and the accessory cells of the tumor microenvironment. They emerge via both classical and direct pathways and actively participate in tumor colonisation of distant tissues. The proteins, nucleic acids, cytokines and ...

Tumour-derived exosomes (TEX) are a subset of extracellular vesicles (EVs) present in body fluids of patients with cancer. The role of this exosome subset in melanoma progression has been of interest ever since ex vivo studies of exosomes produced by ...