MetroHealth Research Institute scientist Khalid Sossey-Alaoui, PhD, has been awarded a five-year, $3.3 million grant from the National Institutes of...
Read More »Extracellular vesicles deliver lncRNA signals that promote lung cancer metastasis
Extracellular vesicles deliver lncRNA ROLLCSC to lung cancer cells, reshaping lipid metabolism, suppressing ferroptosis, and promoting metastatic...
Read More »Early release of tumor exosomes in ductal carcinoma in situ
Tumor derived extracellular vesicles spread systemically during early DCIS, altering distant organ gene expression before invasion and highlighting exosomes as potential drivers of premetastatic...
Read More »Researchers aim to disrupt breast cancer line of communication and prevent spread
Neutrophil-derived extracellular vesicles shaped by a cholesterol metabolite drive breast cancer cells toward chemoresistance and metastasis, revealing...
Read More »Mesenchymal colorectal cancers show unique extracellular vesicle profiles that could enable liquid biopsy diagnostics
Extracellular vesicles from mesenchymal colorectal cancers show distinct RNA and protein cargo, offering potential for subtype-specific, noninvasive liquid biopsy diagnostics...
Read More »Extracellular Vesicles: How the Body’s Text Message System Affects Health and Disease
Extracellular vesicles and exosomes act as the body’s molecular messengers, influencing immune responses, cancer metastasis, and inflammation...
Read More »Extracellular vesicles in cancer´s communication: messages we can read and how to answer
Extracellular vesicles help cancer cells communicate and survive by carrying proteins and genetic material. RNA sequencing and biomarker research...
Read More »New study could reshape our understanding of how cancer spreads
Extracellular vesicles called shearosomes are released by circulating tumor cells as they squeeze through capillaries, influencing blood vessels and...
Read More »Concurrent inhibition of tumor growth and metastasis by a lipidated nanophotosensitizer tracing and disabling tumor extracellular vesicles
Targeting extracellular vesicles with light-activated lipid nanoparticles blocks cancer’s ability to spread, offering a new strategy to suppress both tumor...
Read More »WCM scientists receive inaugural Pershing Square Foundation Ovarian Cancer Challenge Grant
Researchers have developed a light-controlled nanomotor made from extracellular vesicles and gene-silencing molecules that penetrates the skin to fight...
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