Tag Archives: Microenvironment

The role of exosomes in cancer drug-resistance

exosomes

Chemotherapy, one of the principal approaches for cancer patients, plays a crucial role in controlling tumor progression. Clinically, tumors reveal a satisfactory response following the first exposure to the chemotherapeutic drugs in treatment. However, most tumors sooner or later become ...

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Circulating exosomes cause tumor malignancy in a chronic sleep fragmentation model

exosomes

Chronic sleep fragmentation (SF) increases cancer aggressiveness in mice. Exosomes exhibit pleiotropic biological functions, including immune regulatory functions, antigen presentation, intracellular communication and inter-cellular transfer of RNA and proteins. University of Chicago researchers hypothesized that SF-induced alterations in biosynthesis and ...

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