Researchers are engineering extracellular vesicles from stem cell-derived microglia to reduce brain inflammation and promote tissue repair, potentially...
Read More »Alzheimer’s – a Nasal Spray Protects Neurons and Memory
Human amniotic extracellular vesicles delivered intranasally reached the brain, reduced neuroinflammation, supported synaptic function, and improved memory in experimental models of...
Read More »Scientists reverse brain aging, with a nasal spray
Intranasal extracellular vesicles therapy reduces neuroinflammation by modulating microglial signaling pathways, improving mitochondrial function and cognitive performance in aging brain models...
Read More »Using extracellular vesicles and AI to improve diagnosis of depression and bipolar disorder
Extracellular vesicles combined with AI-driven imaging of microglia enable accurate differentiation between depression and bipolar disorder, offering...
Read More »Harvest time-dependent changes in the composition and function of microglia-derived small extracellular vesicles
Extracellular vesicles released by microglia change their molecular cargo over time, with later harvests carrying more RNA and proteins linked to stress and neurodegeneration, highlighting the importance of...
Read More »Extracellular vesicles help reduce inflammation and improve recovery after brain injury
Extracellular vesicles from mesenchymal stromal cells reduce inflammatory proteins in aged monkeys after brain injury, promoting improved motor...
Read More »Human breast milk-derived exosomes – a potential shield against neuroinflammation in preterm infants
Microglia are specialized immune cells in the brain that play a crucial role in responding to infections and injuries. In the case of bacterial infections, like those caused by lipopolysaccharide (LPS), microglia...
Read More »Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain
Neuroinflammation, a major player in neurodegenerative diseases such as Alzheimer's and Parkinson's, is closely linked to aging. Despite extensive research, effective treatments for neuroinflammation remain elusive. However, recent findings offer hope. In aging brains, particularly...
Read More »Nasal spray made from stem cell-derived extracellular vesicles could treat Alzheimer’s disease
A new therapy may delay Alzheimer’s disease progression by years, according to a study by researchers at Texas A&M University College of Medicine. Published in the Journal of Extracellular Vesicles, the research aims to explore treatment...
Read More »Cell-to-cell communication by microglia related extracellular vesicles
Extracellular vesicles, including exosomes and microvesicles, are small, nano-to-micrometer vesicles that are released from cells. While initially observed in immune cells and reticulocytes as vesicles meant to remove archaic proteins, now they have been observed in almost all cell types ...
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