Extracellular vesicles, including exosomes and microvesicles, are small, nano-to-micrometer vesicles that are released from cells. While initially observed in immune cells and reticulocytes as vesicles meant to remove archaic proteins, now they have been observed in almost all cell types ...
Read More »Circulating exosomes may act as a neuroinflammatory mediator in systemic inflammation
Neuroinflammation is implicated in the development and progression of many neurodegenerative diseases. Conditions that lead to a peripheral immune response are often associated with inflammation in the central nervous system, suggesting a...
Read More »Post-doc Position Available – Laboratory of Molecular NeuroTherapeutics
We are looking for highly motivated postdoctoral research fellows with a PhD in molecular biology and neuroscience field awarded within the past three years. These positions will be involved in functional characterization of extracellular vesicles (such as exosomes) in Alzheimer’s ...
Read More »Exosomes can diffuse throughout the brain and may play a role in the dynamics of amyloid deposition in Alzheimer’s disease through microglia
Exosomes, a type of extracellular vesicle, have been shown to be involved in many disorders, including Alzheimer’s disease (AD). Exosomes may contribute to the spread of misfolded proteins such as amyloid-β (Aβ) and α-synuclein. However, the specific diffusion process of ...
Read More »Post-doc Postion Available – Med Laboratory of Molecular Neurotherapeutics
We are looking for highly motivated postdoctoral research fellows with a PhD in molecular biology and neuroscience field awarded within the past three years. These positions will be involved in functional characterization of extracellular vesicles (such as exosomes) in Alzheimer’s ...
Read More »Depletion of microglia and inhibition of exosome synthesis halt tau propagation
Deadly Delivery – Microglia May Traffic Tau Via Exosomes
from Alzforum – Researchers have known for some time that the tau protein wears walking shoes; it can pass between neurons and march across interconnected regions of the brain. Microglial journeymen may facilitate these interneuronal excursions, according to a study ...
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