Extracellular vesicles (EVs) are commonly studied by flow cytometry. Due to their small size and low refractive index, the scatter intensity of most EVs...
Read More »Nomenclature – extracellular vesicles or exosomes?
Usage and rate of increase of common EV terms in PubMed-indexed articles A major focus of the recently updated guidelines of the International Society for Extracellular Vesicles (ISEV) on...
Read More »miRandola 2017 – a curated knowledge base of non-invasive biomarkers
A team led by researchers at the University of Copenhagen has created miRandola, a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the relevance of ncRNAs as non-invasive biomarkers. An increasing amount of experimental evidence ...
Read More »High-resolution flow cytometric sorting of different EV subsets
Submicron-sized vesicles released by cells are increasingly recognized for their role in intercellular communication and as biomarkers of disease. Methods for high-throughput, multi-parameter analysis of such extracellular vesicles (EVs) are crucial to further investigate their diversity and function. Researchers at ...
Read More »Isolation and characterization of platelet-derived extracellular vesicles
Platelet-derived extracellular vesicles (EVs) participate, for example, in haemostasis, immunity and development. Most studies of platelet EVs have targeted microparticles, whereas exosomes and EV characterization under various conditions have been less analyzed. Studies have been hampered by the difficulty in ...
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