Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and eukaryotic cells and play a vital role in intercellular communication. EVs are classified into several subtypes based on their origin, physical characteristics, and biomolecular...
Read More »High-resolution imaging flow cytometry reveals impact of incubation temperature on labeling of extracellular vesicles with antibodies
Extracellular vesicles (EVs) are released from basically all cells. Over the last decade, small EVs (sEVs; 50-150 nm) have gained enormous attention in diagnostics and therapy. However, methodological limitations coupled to the lack of EV standards leave...
Read More »Liquid Biopsy as Novel Tool in Precision Medicine
In recent years, there has been an increase in knowledge of cancer, accompanied by a technological development that gives rise to medical oncology. An instrument that allows the...
Read More »Circulating extracellular vesicles for the diagnosis and dynamic risk profiling of alcoholic hepatitis
Alcoholic hepatitis (AH) is diagnosed by clinical criteria, although several objective scores facilitate risk stratification. Extracellular vesicles (EVs) have emerged as novel biomarkers for many diseases and are also implicated in the pathogenesis of AH...
Read More »Progress in extracellular vesicle biology and their application in cancer medicine
Under the broader category of extracellular vesicles (EVs), exosomes are now well recognized for their contribution and potential for biomedical research. During the last ten years, numerous technologies for purification and characterization of EVs have been developed. This enhanced knowledge has ...
Read More »Inhibiting extracellular vesicles formation and release
It is now becoming well established that vesicles are released from a broad range of cell types and are involved in cell-to-cell communication, both in physiological and pathological conditions. Once outside the cell, these vesicles are termed extracellular vesicles (EVs). ...
Read More »Generation, Purification and Engineering of Extracellular Vesicles and Their Biomedical Applications.
Extracellular vesicles (EVs), derived from cell membranes, demonstrate the potential to be excellent therapeutics and drug carriers. Although EVs are promising, the process to develop high-quality...
Read More »Extracellular vesicles – a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and other biofluids of cancer patients. They carry various tumor-derived molecules such as mutated DNA and RNA fragments...
Read More »Engineered Extracellular Vesicles and Their Mimetics for Clinical Translation
Cells secrete extracellular vesicles (EVs) to external environments to achieve cellular homeostasis and cell-to-cell communication. Their therapeutic potential has been constantly spotlighted since they mirror both cytoplasmic and membranous...
Read More »Scientists unlock secrets of maternal/fetal cellular communication during pregnancy
Researchers have unlocked mysteries surrounding how a pregnant mother’s cells and her fetus’ cells communicate throughout pregnancy. With this new information, The University of Texas Medical Branch at Galveston team and their colleagues in South...
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