Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are smaller intracellular membrane nanoparticle vesicles...
Read More »PureTech Health Exclusively Licenses Novel Milk-Derived Exosome Technology
PureTech Health plc, an advanced, clinical-stage biopharmaceutical company, today announced an exclusive licensing agreement with 3P Biotechnologies, Inc., via University of Louisville, for an exosome-based technology (Calix) for the oral administration of biologics, nucleic acids, and complex small molecules. The ...
Read More »Exosomes in Human Breast Milk Promote EMT
Pregnancy increases breast cancer risk for all women for at least 5 years after parturition. During weaning and involution the breast microenvironment becomes tumor promotional. Exosomes provide cell-cell communication during physiologic processes such as lactation, but also in breast cancer. ...
Read More »Human vascular endothelial cells transport foreign exosomes from cow’s milk and deliver the microRNA cargo to peripheral tissues
Encapsulation of microRNAs in exosomes confers protection against degradation and a vehicle for shuttling of microRNAs between cells and tissues, and cellular uptake by endocytosis. Exosomes can be found in foods including milk. Humans absorb cow’s milk exosomes and deliver ...
Read More »MicroRNA expression profiles of bovine milk exosomes
Milk exosomes are a rich source of microRNAs (miRNAs) that are protected from degradation. Ingestion of milk and subsequent absorption of miRNAs into recipient cells by endocytosis may play a role in the regulation of neonatal innate and adaptive immunity. ...
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