Tag Archives: miR-21*

Researchers from the Chengdu University of Traditional Chinese Medicine set out to assess a new and highly specific, but low-cost, easily performed and suitable for large-scale applications method...

Following peripheral axon injury, dysregulation of non-coding microRNAs (miRs) occurs in dorsal root ganglia (DRG) sensory neurons. Researchers from King’s College London show that DRG neuron cell bodies release extracellular vesicles, including exosomes containing miRs, upon activity. They demonstrate that ...

Exosomes, the natural vehicles of intercellular communication, transfer proteins, mRNAs and microRNAs (miRNAs) and mediate many physiological and pathological processes. It is not clear that whether exosomal miRNAs could regulate gene expression across species, though some studies suggest interactions of ...

Bystander effects can be induced through cellular communication between irradiated cells and non-irradiated cells. The signals that mediate this cellular communication, such as cytokines, reactive oxygen species, nitric oxide and even microRNAs, can be transferred between cells via gap junctions ...

Recent studies have found that extracellular vesicles (EVs) play an important role in normal and disease processes. In their recent study, a team of scientists led by researchers from the University of Nebraska Medical Center isolated and characterized EVs from ...

Researchers from the University of Nebraska Medical Center isolated and characterized EVs from the brains of rhesus macaques, both with and without simian immunodeficiency virus (SIV) induced central nervous system (CNS) disease. Small RNA sequencing revealed increased miR-21 levels in EVs ...

In response to stress, the heart undergoes extensive cardiac remodeling that results in cardiac fibrosis and pathological growth of cardiomyocytes (hypertrophy), which contribute to heart failure. Alterations in microRNA (miRNA) levels are associated with dysfunctional gene expression profiles associated with ...