Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...
Read More »Ymir Genomics & (OHSU) announce a licensing agreement and patent application covering miRNA biomarkers discovered utilizing Ymir’s extracellular vesicle isolation technology
Ymir Genomics LLC (Ymir) and the Oregon Health & Science University (OHSU) Knight Cancer Institute today announced a licensing agreement and filed patent application that seeks to protect and promote newly-discovered high value urinary biomarkers for detecting cirrhosis and/or hepatocellular ...
Read More »Therapeutic miRNA-enriched extracellular vesicles
Extracellular vesicles (EVs) are 50–300 nm vesicles secreted by eukaryotic cells. They can carry cargo (including miRNA) from the donor cell to the recipient cell. miRNAs in EVs can change the translational profile of the recipient cell and modulate cellular ...
Read More »Urinary exosome based, non-invasive prostate cancer test validated
miR Scientific, LLC, a healthcare company whose purpose is to transform cancer management by providing early and highly accurate detection, characterization and monitoring of disease, today announced the publication of validation data...
Read More »Researchers identify exosomal microRNA that shows promise for hair regrowth
Researchers from North Carolina State University have identified a microRNA (miRNA) that could promote hair regeneration. This miRNA – miR-218-5p – plays an important role in regulating the pathway involved in follicle regeneration, and could be a...
Read More »Tear exosomes – a potential source of diagnostic and prognostic biomarkers for metastatic breast cancer
Exosomes are produced by normal and cancer cells. Exosomes are found in the serum of cancer patients and have been used for diagnosis and prognosis. Recently tears from non-cancer patients have been found to contain exosomes. In the present report ...
Read More »Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood
Researchers at the University of Genoa aimed to explore the involvement of miRNAs in beneficial effects exerted by physical activity in breast cancer prevention.The levels of extracellular miRNAs were evaluated in blood plasma before and after structured...
Read More »New discovery reveals that glioblastoma acquires radiation resistance by jettisoning exosomal microRNAs
In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. Investigators at the University of Minnesota showed that cancer cells perform similar feats in escaping...
Read More »miR-26a regulates extracellular vesicle secretion from prostate cancer cells
Extracellular vesicles (EVs) are involved in intercellular communication during cancer progression; thus, elucidating the mechanism of EV secretion in cancer cells will contribute to the development of an EV-targeted cancer treatment...
Read More »Loss of an important tumor-suppressing gene allows head and neck cancer to recruit and reprogram nerves to fuel tumor growth
Loss of an important tumor-suppressing gene allows head and neck cancer to spin off signals to nearby nerves, changing their function and recruiting...
Read More »