A molecule that helps blood clot may also play a role in multiple sclerosis relapses, researchers report in the May 6 issue of PNAS. The new research may help answer the mystery of why remissions...
Read More »Small vesicles involved in MS seen to be affected by gilenya, suggesting potential as biomarker
Gilenya (fingolimod) influences the release and function of small membrane particles, called extracellular vesicles, that are involved in the...
Read More »The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, in which myelin and oligodendrocytes are the main targets recognized...
Read More »Delivering multiple sclerosis drugs to the brain in extracellular vesicles
Researchers from the department of anatomy and cell biology in the UIC College of Medicine have received a seed grant to develop a new drug...
Read More »Exosomal microRNA signatures in multiple sclerosis reflect disease status
A breakthrough study led by the University of Sydney’s Brain and Mind Centre and Royal Prince Alfred Hospital has revealed unique molecules in the blood of people with Multiple Sclerosis (MS) that could become definitive diagnostic biomarkers of the world’s ...
Read More »Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases
Extracellular vesicles (EVs) can be classified into apoptotic bodies, microvesicles (MVs), and exosomes, based on their origin or size. Exosomes are the smallest and best characterized vesicles which derived from the endosomal system. These vesicles are released from many different ...
Read More »Global Exosome Transcriptome Profiling Reveals Biomarkers for Multiple Sclerosis
Accumulating evidence supports a role for exosomes in immune regulation. In this study, researchers from the Medical University of Lodz investigated the total circulating exosome transcriptome in relapsing-remitting multiple sclerosis patients (RRMS) and healthy controls (HC). Next generation sequencing (NGS) ...
Read More »Candidate biomarker of multiple sclerosis found in extracellular vesicles isolated from plasma
Extracellular vesicles (EVs) are membrane nanovesicles of diverse sizes secreted by different cell types and are involved in intercellular communication. EVs shuttle proteins, nucleic acids, and lipids that reflect their cellular origin and could mediate their biological function in recipient ...
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