Exosomes have many biological functions as short- and long distance nanocarriers for cell-to-cell communication. They allow the exchange of complex information between cells, and thereby modulate...
Read More »The challenges and possibilities of extracellular vesicles as therapeutic vehicles
Extracellular vesicles (EVs) are small lipid-enclosed particles that can carry various types of cargo, including proteins, nucleic acids and metabolites...
Read More »Targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity
The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced in 2011 and has since then gained increasing attention as promising new candidates in the field. Targeting EVs to areas of disease can be achieved through ...
Read More »Surface modification of gold nanoparticles with neuron-targeted exosome for enhanced blood-brain barrier penetration
Gold nanoparticles (AuNPs) have been extensively used as nanomaterials for theranostic applications due to their multifunctional characteristics in therapeutics, imaging, and surface modification. In this...
Read More »Isolation of exosome-like nanoparticles and analysis of microRNAs derived from coconut water based on small RNA-Seq
In this study, researchers from Tongji University identifed the presence of microRNAs in coconut water by real-time polymerase chain reaction (PCR) based on the results of high-throughput small RNA...
Read More »Scientists unlock path to use cell’s own nanoparticles as disease biomarkers
Researchers at the University of Sydney have established a method to identify individual nanoparticles released by human cells, opening...
Read More »Isolation of exosome-like nanoparticles and analysis of microRNAs derived from coconut water
In this study, researchers at Tongji University identified the presence of microRNAs in coconut water by real-time PCR based on the results of high-throughput small RNA sequencing. In addition, the differences in microRNA content between immature and mature coconut water ...
Read More »Absolute sizing and label-free identification of extracellular vesicles by flow cytometry
Here, University of Amsterdam researchers present a new method, named flow cytometry scatter ratio (Flow-SR), to relate the ambiguous light scattering signals of flow cytometry to the diameter and refractive index (RI) of single nanoparticles between...
Read More »Researchers invent novel RNA nanotech to decorate exosomes for effective cancer therapy
Therapies based on RNA, such as small interfering RNA, hold great promise for cancer treatment but delivering these agents to their targets in cancer...
Read More »Doctoral student position with grant available – understanding RNA transfer into cells using exosomes and lipid based nanoparticles
Karolinska Institutet, Institutionen för laboratoriemedicin The Department of Laboratory Medicine consists of 9 divisions and is active in many areas of Laboratory Medicine. The department is involved in advanced basic scientific, clinical and epidemiological research. The department is one of ...
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