Researchers developed extracellular vesicles-inspired fluorescent nanovesicles that detect hydrostatic pressure, offering new opportunities to measure pressure changes in biological tissues and complex aqueous environments...
Read More »Pomegranate nanovesicles show promise for treating acute pancreatitis
Extracellular vesicles derived from pomegranate reduce inflammation and oxidative stress, helping preserve pancreatic function and improve...
Read More »Engineering minimal extracellular vesicle mimetics to decode surface protein function
A cell-free platform engineers artificial extracellular vesicles to systematically test how individual surface proteins control uptake and function, advancing...
Read More »Bioengineered extracellular vesicle-mimetic nanovesicles can serve as a powerful instrument to effectively deliver lncRNA
Diabetic wounds, one of the most enervating complications of diabetes mellitus, affect millions of people worldwide annually. Vascular insufficiency, caused by hyperglycemia, is one of the primary causes...
Read More »Bioinspired artificial nanodecoys for hepatitis B virus
Researchers from Xiamen University present a facile route for fabricating a new class of nanomimics that overexpress hepatitis B virus (HBV) receptor by a natural biosynthetic procedure against HBV...
Read More »Improved productive loading onto extracellular vesicles
Extracellular vesicles are promising delivery vesicles for therapeutic RNAs. Small interfering RNA (siRNA) conjugation to cholesterol enables efficient and reproducible loading of extracellular vesicles with...
Read More »Extracellular vesicles could be personalized drug delivery vehicles
Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous — their own — immune cells to ...
Read More »Biological functions, isolation and detection strategies for exosomes
Exosomes are nanoscale (≈30-150 nm) extracellular vesicles of endocytic origin that are shed by most types of cells and circulate in bodily fluids. Exosomes carry a specific composition of proteins, lipids, RNA, and DNA and can work as cargo to ...
Read More »Cell-derived drug delivery systems
Schematic demonstrating the production of CDNs. CDNs can be produced “on-demand” in larger quantities within a shorter time frame than isolating the same amount of exosomes...
Read More »Cell derived nanovesicles could provide a cost-effective alternative to exosomes as an ideal drug nanocarrier
Cell Derived Nanovesicles (CDNs) have been developed from the rapidly expanding field of exosomes, representing a class of bioinspired Drug Delivery Systems (DDS). However, translation to clinical applications is limited by the low yield and multi-step approach in isolating naturally ...
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