Tag Archives: Neurodegenerative Disease

Exosomes, microscopic packets containing genetic material, are shed by tissues into the blood. By sequencing microRNA within exosomes originating in the brain, it is now possible to definitively distinguish blood samples of ALS patients from healthy controls...

Exosomes are a heterogenous subpopulation of extracellular vesicles 30–150 nm in range and of endosome-derived origin. Despite more than 30 years of research that followed their definition and indicated their important role in cellular...

Huntington’s disease (HD) is a genetic neurodegenerative disease that is caused by abnormal CAG expansion. Altered microRNA (miRNA) expression also causes abnormal gene regulation in this neurodegenerative disease. The delivery of abnormally downregulated miRNAs might restore normal gene regulation and ...

Postdoctoral Fellow to Study Exosomes in Neurodegenerative Disease The Johns Hopkins University School of Medicine We are seeking a highly motivated individual for a postdoctoral scholar position in the Department of Neurology at the Johns Hopkins University School of Medicine. ...

Recent findings indicate that the beneficial effects of adipose stem cells (ASCs), reported in several neurodegenerative experimental models, could be due to their paracrine activity mediated by the release of exosomes. The aim of this study was the development and ...

Exosomes, nano-sized extracellular vesicles secreted by most cell types, are found everywhere in the body. The role of exosomes in cellular functions has in the past years developed from being considered little more than cellular trashcans, to being proven important ...

Exosomes, a group of vesicles originating from the multivesicular bodies (MVBs), are released into the extracellular space when MVBs fuse with the plasma membrane. Numerous studies indicate that exosomes play important roles in cell-to-cell communication, and exosomes from specific cell ...

Postdoctoral Fellow to Study Exosomes in Neurodegenerative Disease. The Johns Hopkins University School of Medicine.We are seeking a highly motivated individual for a postdoctoral scholar position in the Department of Neurology at the Johns Hopkins University School of Medicine. We ...