Tag Archives: neurological disorders

Extracellular vesicles could provide natural delivery vehicles for transporting therapeutic cargo from the nasal cavity to the brain while helping bypass the blood-brain barrier...

Researchers at KIST developed a cubosome-based method for rapidly loading large biomolecules into extracellular vesicles, enabling efficient, targeted drug delivery, even across the blood-brain barrier...

Exosomes offer a biocompatible way to cross the blood-brain barrier and deliver RNA sequencing-based therapies, holding promise for treating neurological diseases with improved precision and safety...

Engineered extracellular vesicles can now efficiently deliver gene editors and therapeutic proteins into cells, offering a promising new approach for treating genetic diseases and inflammatory conditions...

This study reveals that extracellular vesicles carry the endocannabinoid 2-AG between brain cells, uncovering a new mode of neural communication...

Researchers, led by Mario van der Stelt, discovered that 2-AG, a naturally occurring compound similar to marijuana, is transported via extracellular vesicles in the brain, offering new insights into how the brain communicates. This breakthrough could lead to novel...

Scientists at Mount Sinai have developed lipid nanoparticles that can safely and efficiently deliver mRNA across the blood-brain barrier. This breakthrough could enable mRNA-based therapies for neurological disorders and opens new possibilities...

They might not make you beautiful, but research suggests exosomes might help us diagnose and treat diseases. You might have seen them advertised—they’re being touted as a hot new beauty...

Delivery represents a significant barrier to the clinical advancement of oligonucleotide therapeutics for the treatment of neurological disorders, such as Huntington’s disease. Small, endogenous vesicles known as exosomes have the potential to act as oligonucleotide delivery vehicles, but robust and ...

Adult neurogenesis has been convincingly demonstrated in two regions of the mammalian brain: the sub-granular zone (SGZ) of the dentate gyrus (DG) in the hippocampus, and the sub-ventricular zone (SVZ) of the lateral ventricles (LV). SGZ newborn neurons are destined ...