Exosomes are Extracellular Vesicles (EV) that own unique structural features and functions and have gradually become the hot research spot in recent...
Read More »AACR 2019: Liquid Biopsy–Based Test May Be Reliable in Identifying Treatment for Non–Small Cell Lung Cancer
The number of guideline-recommended biomarkers to be assessed in patients with newly diagnosed, metastatic non–small cell lung cancer (NSCLC) is increasing. These biomarkers include both predictive...
Read More »Exosomal lipids for classifying early and late stage non-small cell lung cancer
Lung cancer is the leading cause of cancer deaths in the United States. Patients with early stage lung cancer have the best prognosis with surgical...
Read More »Blood-based tumor biomarkers in lung cancer for detection and treatment
The therapeutic landscape of lung cancer has expanded significantly over the past decade. Advancements in molecularly targeted therapies, strategies to discover and treat resistance mutations, and development of personalized cancer treatments in the context of tumor heterogeneity and dynamic tumor ...
Read More »Liquid Biopsy: Differences Among Technologies
Sandip Patel, MD, and Geoffrey R. Oxnard, MD, discuss differences among platforms for genetic profiling of metastatic non–small cell lung cancer in terms of sensitivity, specificity, and multiplex capability, as well as detection of complex genomic alterations.
Read More »Biocept and UT Southwestern Announce Liquid Biopsy Clinical Study to Profile Lung Cancer Patients
Biocept, Inc. a leading commercial provider of liquid biopsy tests designed to provide physicians with clinically actionable information to improve the outcomes of cancer patients, announces it has entered into a clinical study agreement with the University of Texas Southwestern Medical Center ...
Read More »Exosomal microRNA in plasma as a non-invasive biomarker for the recurrence of non-small cell lung cancer
Exosome images captured by transmission electron microscope. Original magnification, ×25,000 Predictive biomarkers for the recurrence of non-small cell lung cancer (NSCLC) in patients who have received curative resection are important for cancer treatment. The functional microRNAs (miRNAs/miRs) in the exosomes ...
Read More »UCLA Dentistry receives a $2.5 million grant from the National Cancer Institute to clinically validate liquid biopsy test
Researchers will partner with the UCLA Department of Pathology to make detection of non-small cell lung cancer more accurate and easier to detect with a saliva sample Lung cancer is a leading cause of cancer death among men and women. ...
Read More »Exosomal proteins as prognostic biomarkers in non-small cell lung cancer
Use of exosomes as biomarkers in non-small cell lung cancer (NSCLC) is an intriguing approach in the liquid-biopsy era. Exosomes are nano-sized vesicles with membrane-bound proteins that reflect their originating cell. Prognostic biomarkers are needed to improve patient selection for ...
Read More »Liquid biopsy based biomarkers in non-small cell lung cancer for diagnosis and treatment monitoring
Advances in the knowledge of the biology of non-small cell lung cancer (NSCLC) have revealed molecular information used for systemic cancer therapy targeting metastatic disease, with an important impact on patients overall survival (OS) and quality of life. However, a ...
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