Tag Archives: Obesity

Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory...

Obesity is a global public health issue with serious health consequences and rising prevalence. It is a risk factor for a broad range of diseases, particularly atherosclerosis and cardiovascular disease. Long-term weight loss is difficult to achieve, even with diet, ...

Milk consumption is a hallmark of western diet. According to common believes, milk consumption has beneficial effects for human health. Pasteurization of cow's milk protects thermolabile vitamins and other organic compounds including bioactive and...

Obesity-associated metabolic dysfunctions are linked to dysregulated production of adipokines. Accumulating evidence suggests a role for fat-derived extracellular vesicles (EVs) in obesity-metabolic disturbances. Since EVs convey numerous proteins, Angers University researchers aimed to evaluate their contribution in adipokine secretion. The ...

Researchers at the University of Texas Southwestern Medical Center have uncovered the existence of extracellular vesicle (EV)-mediated signaling between cell types within the adipose tissue (AT) proper. This phenomenon became evident in their...

Preliminary result holds the promise of helping avert chronic disease in the next generation of children Exosomes isolated from very obese patients behave very differently than those derived from lean patients and may be key players in heightening youths’ likelihood ...

Losing weight through surgical approaches appears to reset chemical messages that fat cells send Children’s National Health System Losing weight appears to reset the chemical messages that fat cells send to other parts of the body that otherwise would encourage ...

New research has identified a novel mode of communication between adipocytes and cancer cells that regulates tumour aggressiveness. Adipocyte exosomes (ad-exos) purified from conditioned medium of 3T3-F442A mature adipocytes increased melanoma cell migration and invasion in vitro. Analysis of the ...

Obesity is frequently complicated by comorbid conditions, yet how excess adipose contributes is poorly understood. Although adipocytes in obese individuals induce systemic inflammation via secreted cytokines, another potential mediator has recently been identified (i.e. adipocyte-derived exosomes). We hypothesized that adipocyte-derived ...