Researchers of the Neurobiology and Neurophysiology team of the Medicine Faculty at Valencia Catholic University (UCV), headed by Jorge Bacia, have discovered that exosomes – microscopic extracellular vesicles that are released by all cells...
Read More »Exosomal Biomarkers In Down Syndrome And Alzheimer’s Disease
Every person with Down syndrome (DS) has the characteristic features of Alzheimer’s disease (AD) neuropathology in their brain by the age of forty, and most go on to develop AD dementia. Since people with DS show highly variable levels of ...
Read More »Melatonin treatment enhances therapeutic effects of exosomes
A team led by researchers at I-Shou University School of Medicine tested the hypothesis that combined melatonin and exogenic adipose mesenchymal stem cell (ADMSC)-derived exosome treatment offers superior protection against liver ischemia-reperfusion (LIR) injury compared to either alone. In vitro studies ...
Read More »Cigarette smoke extract induced exosome release
Airway epithelial cells have been described to release extracellular vesicles (EVs) with pathological properties when exposed to cigarette smoke extract (CSE). As CSE causes oxidative stress, researchers from Maastricht University Medical Center investigated whether its oxidative components are responsible for ...
Read More »Exosomes as drug delivery vehicles for Parkinson’s disease therapy
Exosomes are naturally occurring nanosized vesicles that have attracted considerable attention as drug delivery vehicles in the past few years. Exosomes are comprised of natural lipid bilayers with the abundance of adhesive proteins that readily interact with cellular membranes. Researchers ...
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