Tag Archives: pancreatic cancer

Liquid biopsy-based biomarkers, including microRNAs packaged within extracellular vesicles, are promising tools for patient management. The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is related to PCa progression and is found in the semen of patients with PCa. ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most intractable malignancy, with an only 6% 5-year relative survival rate. The dismal therapeutic effect is attributed to the chemotherapy resistance and unique pathophysiology with abundant inflammatory cytokines and abnormal hyperplasia of ...

Tumor-derived exosomes play important roles in tumor metastases. In this report, researchers at Gifu University School of Medicine observed the fate of tumor-derived exosomes in pancreatic cancer metastatic nude-mouse models using color-coded imaging...

Osaka University researchers base biomarker detection and targeted therapy on the same protein from pancreatic cancer patients Of all gastrointestinal cancers, pancreatic cancer is one...

An image depicting the essentials of new ASU research was used as the cover of the Theranostics issue that published the study; it portrays...

We are seeking a talented and passionate postdoc who has a strong interest in cancer biology. The qualified candidate will study the impact that exosomes derived from the tumor microenvironment have on pancreatic cancer initiation, progression, and therapeutic resistance using 2D and 3D cell cultures...

Pancreatic ductal adenocarcinoma (PDAC) typically has nonspecific symptoms and is often found too late to treat. Because diagnosis of PDAC involves complex, invasive, and expensive procedures, screening populations at increased risk will depend on...

Circulating exosomes contain a wealth of proteomic and genetic information, presenting an enormous opportunity in cancer diagnostics. While microfluidic approaches have been used to successfully isolate cells from complex samples, scaling these approaches for exosome isolation has been limited by ...

Detection of circulating tumor DNA (ctDNA) can be limited due to their relative scarcity in circulation, particularly while patients are actively undergoing therapy. Exosomes provide a vehicle through which cancer-specific material can be enriched from the compendium of circulating non-neoplastic ...

Exosomes (Exo), powerful intercellular communicators, are recovered in all body fluids, suggesting suitability for diagnosis and prognosis. Easy in vitro manipulation recommends Exo as drug vehicles. Aiming to consolidate diagnostic and therapeutic potential of Exo, researchers from the University Hospital of ...